Malgorzata Benedyk-Machaczka has defended her PhD in 2007 at the Faculty of Chemistry and Pharmacy at the University of Muenster, Germany. In 2011, after completing a post-doc at Institute of Immunology at University of Muenster, Germany, she joined the Faculty of Biochemistry, Biophysics and Biotechnology of the Jagiellonian University in Krakow as a scholarship holder in the Team program (FNP). Her scientific interests are focused on the use of animal models in the study of mechanisms underlying the clinical and epidemiological links between periodontitis (parodontosis, PD) and bacteria responsible for PD (Porphyromonas gingivalis, Pg), and human systemic diseases. In her research, she has demonstrated the importance of cysteine ​​proteases (gingipain) and peptidylarginine deiminase (PPAD) secreted by Pg, as the main virulence factors responsible for pathological changes and mortality in aspiration pneumonia, accelerated development and severe state of arthritis rheumatoid arthritis (RA) in mice infected with Pg. Recently, using various infection models (subcutaneous chambers, oral bacterial administration and thread-binding of teeth), she is conducting studies to show that Pg by gingipain secretion causes pathological changes in the brain of mice similar to those observed in Alzheimer's disease.